Mezo, a Bitcoin-native lending protocol, will collaborate with Aerodrome Finance to support trading activity for its MEZO token and Bitcoin-backed stablecoin on the Base network. In a Thursday announcement, Mezo said it will allocate 2.25% of its MEZO supply to Aerodrome’s vote-escrow (veAERO) participants, inviting those users to direct funds into MEZO trading pairs. The program aims to increase activity around MEZO and its USD-backed stablecoin, MUSD. Aerodrome is a Base liquidity provider built by the team behind Optimism.
The partnership links Base-based traders with a newer group of Bitcoin-focused applications as developers explore adapting DeFi models to Bitcoin. Mezo, which allows users to borrow against their Bitcoin holdings, said it has issued more than 2,000 loans and moved roughly $23 million in Bitcoin-denominated assets from Ethereum. The move gives Mezo access to a large and active DeFi user base on the Base network. On Base, infrastructure such as Aerodrome can help support more consistent trading in new tokens and stablecoins.
Bitcoin-based DeFi activity has picked up since 2024, with a growing number of platforms aiming to bring lending, borrowing and yield strategies to the network. Recent examples include Lombard, which is building Bitcoin-based lending infrastructure and has teamed with Bitwise to allow institutional investors to earn yield and borrow against their Bitcoin holdings. Another project, Hashi, has recently launched on the Sui network with early participation from BitGo, Bullish and FalconX, among others. The platform enables users to earn yield on Bitcoin through on-chain lending and borrowing.















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